MARCHIONESS COLOMBI

\mˈɑːʃənˌɛs kˈɒləmbˌa͡ɪ], \mˈɑːʃənˌɛs kˈɒləmbˌa‍ɪ], \m_ˈɑː_ʃ_ə_n_ˌɛ_s k_ˈɒ_l_ə_m_b_ˌaɪ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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