MANNICH BASES
\mˈanɪʃ bˈe͡ɪsɪz], \mˈanɪʃ bˈeɪsɪz], \m_ˈa_n_ɪ_ʃ b_ˈeɪ_s_ɪ_z]\
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Ketonic amines prepared from the condensation of a ketone with formaldehyde and ammonia or a primary or secondary amine. A Mannich base can act as the equivalent of an alpha,beta unsaturated ketone in synthesis or can be reduced to form physiologically active amino alcohols.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.