HEXAMETHONIUM BROMIDE
\hˌɛksɐmɪθˈə͡ʊni͡əm bɹˈɒma͡ɪd], \hˌɛksɐmɪθˈəʊniəm bɹˈɒmaɪd], \h_ˌɛ_k_s_ɐ_m_ɪ_θ_ˈəʊ_n_iə_m b_ɹ_ˈɒ_m_aɪ_d]\
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A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.