GLYCERINE, GLYCERIN
\ɡlˈɪsəɹˌiːn], \ɡlˈɪsəɹˌiːn], \ɡ_l_ˈɪ_s_ə_ɹ_ˌiː_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.