FRU 6 P,2 KINASE
\fɹˈuː sˈɪks pˈiː tˈuː kˈɪne͡ɪs], \fɹˈuː sˈɪks pˈiː tˈuː kˈɪneɪs], \f_ɹ_ˈuː s_ˈɪ_k_s p_ˈiː t_ˈuː k_ˈɪ_n_eɪ_s]\
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An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.
By DataStellar Co., Ltd
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