ERK2 BRAIN KINASE PK40
\ˌiːˌɑːkˈe͡ɪ tˈuː bɹˈe͡ɪn kˈɪne͡ɪs pˌiːkˈe͡ɪ fˈɔːti], \ˌiːˌɑːkˈeɪ tˈuː bɹˈeɪn kˈɪneɪs pˌiːkˈeɪ fˈɔːti], \ˌiː__ˌɑː_k_ˈeɪ t_ˈuː b_ɹ_ˈeɪ_n k_ˈɪ_n_eɪ_s p_ˌiː_k_ˈeɪ f_ˈɔː_t_i]\
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Extracellular signal-regulated kinase 2. A proline-directed serine/threonine kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to translocation into the nucleus and phosphorylation of certain transcription factors. p40 MAPK and p41 MAPK are isoforms. EC 2.7.10.-.
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