EASTERNMOST
\ˈiːstənmˌə͡ʊst], \ˈiːstənmˌəʊst], \ˈiː_s_t_ə_n_m_ˌəʊ_s_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.