DON ANTONIO GIL Y ZARATE
\dˈɒn antˈə͡ʊnɪˌə͡ʊ ɡˈɪl wˈa͡ɪ zˈaɹe͡ɪt], \dˈɒn antˈəʊnɪˌəʊ ɡˈɪl wˈaɪ zˈaɹeɪt], \d_ˈɒ_n a_n_t_ˈəʊ_n_ɪ__ˌəʊ ɡ_ˈɪ_l w_ˈaɪ z_ˈa_ɹ_eɪ_t]\
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A Spanish dramatist; born in the Escorial, Dec. 1, 1793; died at Madrid, Jan. 27, 1861. Mathematics and physics were his university specialties; but he entered upon a political career when a young man, attaining an important post in the Ministry of the Interior in 1820. The revolutions in Spain forced him out of public life, and he became a professor at the Madrid Lyceum. About this time he turned to playwriting; and a tragedy, "Dona Blanca de Borbon", made his name widely known in 1832. His next efforts were less conventionally classical and more on the romantic order. "Carlos II., the Bewitched", is one of his most celebrated tragedies, but "Guzman the Good" is by far the best. "Rosmunda" and "Don Alvaro de Luna" also stand at the head of the collection of plays that have won for him the premiership of the modern Spanish drama.
By Charles Dudley Warner
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.