DIADEMED

\dˈa͡ɪədˌiːmd], \dˈa‍ɪədˌiːmd], \d_ˈaɪ_ə_d_ˌiː_m_d]\
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1899 - The american dictionary of the english language.
By Daniel Lyons
 
1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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