DESULFOVIRIDINS
\diːsˈʌlfəvˌɪɹɪdˌɪnz], \diːsˈʌlfəvˌɪɹɪdˌɪnz], \d_iː_s_ˈʌ_l_f_ə_v_ˌɪ_ɹ_ɪ_d_ˌɪ_n_z]\
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Hydrogen sulfide: (acceptor) oxidoreductases. Enzymes which reversibly catalyze the oxidation of hydrogen sulfide in the presence of various acceptors to sulfite and a reduced acceptor. EC 1.8.1.2 utilizes NADP+ as the acceptor. EC 1.8.7.1 utilizes oxidized ferredoxin as acceptor and EC 1.8.99.1 will utilize a variety of acceptors.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.