CRETISM

\kɹˈɛtɪzəm], \kɹˈɛtɪzəm], \k_ɹ_ˈɛ_t_ɪ_z_ə_m]\

Definitions of CRETISM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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