CHILTERN HUNDREDS

\t͡ʃˈɪltən hˈʌndɹədz], \t‍ʃˈɪltən hˈʌndɹədz], \tʃ_ˈɪ_l_t_ə_n h_ˈʌ_n_d_ɹ_ə_d_z]\

Definitions of CHILTERN HUNDREDS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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