ASSUMPTION ENDORSEMENT
\ɐsˈʌmpʃən ɛndˈɔːsmənt], \ɐsˈʌmpʃən ɛndˈɔːsmənt], \ɐ_s_ˈʌ_m_p_ʃ_ə_n ɛ_n_d_ˈɔː_s_m_ə_n_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.