ACTS OF TRADE
\ˈakts ɒv tɹˈe͡ɪd], \ˈakts ɒv tɹˈeɪd], \ˈa_k_t_s ɒ_v t_ɹ_ˈeɪ_d]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.